Genetic Testing for Dogs Made Easy

Dog Inherited Disease Testing | Dog's Genetic Risk | EasyDNA USA
Photo provided by Flickr
What is the difference between a blood-based breed identification test and over-the-counter swab DNA tests for dogs?
As opposed to over-the-counter DNA tests for dogs, ROYAL CANIN® Genetic Health Analysis™ is sold exclusively through veterinary clinics. While both types of tests give information about breed mix and optimal weight predictions, the blood test gives additional information about health conditions that the dog may be pre-disposed to as well as nutritional guidelines based on the dog’s breed mix.
Paw Print Genetics - Tag genetic testing for dogs
Photo provided by Pexels
The genetic information used to formulate the enclosed tables and graphs came from DNA samples of 782 dogs from North America, the UK, and Continental Europe. Therefore, we believe that these dogs represent almost all of the genetic diversity that still exists within the breed. This data will be updated as more dogs are tested, so allele and DLA haplotype frequencies may change to a limited extent over time. The breed appears to have reasonable breed-wide diversity, but this diversity is very unbalanced. As a result of genetic bottlenecks traced back to the mid-twentieth century and certain lines, a majority of Standard Poodles are relatively inbred and contain a minority of the existing genetic diversity. This has resulted in an increased incidence of heritable traits, including characterized simple recessive disorders such as PRA, Von Willebrand’s disease, and neonatal encephalopathy; possible recessive disorders such as juvenile renal disease, juvenile cataracts, and enamel dysplasia; and more complex genetic disorders such as autoimmune disease (e.g., SA, AD, IMHA, ITP, thyroiditis, chronic active hepatitis, masticatory myositis), allergies, hip dysplasia, elbow dysplasia, atrial septal defect, patent ductus arteriosus, degenerative myelopathy, and bloat. These various disorders appear to have resulted from both ancient and relatively new mutations that have been concentrated in certain lines as a result of inbreeding. The hope is that breeders will use genetic diversity testing, along with pedigrees, to re-establish genetic diversity across the breed by careful mate selection, while continuing to investigate diseases that appear to have a genetic basis. Genetic Testing for Dogs - San Bruno Pet Hospital
Photo provided by FlickrSan Bruno Pet Hospital is pleased to announce that we now offer DNA-based genetic testing of dogs
Photo provided by FlickrIntegrating Genetic Testing Into Veterinary Practice- Breeding Dogs
Photo provided by Flickr
Mammals have two pigments that are the basis of hair color: eumelanin (black) and pheomelanin (red or yellow). The gene involved in the production of these pigments in many species including dogs is Melanocortin 1 Receptor (MC1R) which is also called Extension. Other genes modify these pigments to produce the variety of colors and patterns found in the domestic dog. The Brown gene, Tyrosinase-Related Protein 1 (TYRP1), is a modifier that dilutes black pigment to brown but does not affect red pigment. Other genes involved in dog coat color include Agouti (ASIP) which organizes the distribution of black and red pigments, Beta-defensin (CBD-103) which is unique to dogs and responsible for dominant black (K locus), and Dilute (MLPH) which dilutes black and red pigments. Other genes that add white patterns and dilute colors are also present in dogs but are specific to certain breeds. Below are expanded descriptions of the genetic tests offered by the Veterinary Genetics Laboratory for dog coat color. Occasionally, skeptics have also tried to test the system by sending DNA samples from the same dog through more than once, under a friend’s name, or they change the gender, said Lytle. Sometimes this can also happen when a dog that’s already been tested by an owner shows up in a shelter that then tests the dog again, or vice versa. Lytle says in these cases, it will pop up as a dog that’s already been analyzed, because each dog’s genetic makeup is unique, like a fingerprint.Years after dog DNA testing was first introduced, though, it's finally becoming mainstream. Since Mars Veterinary launched its dog DNA test in 2007, Wisdom Panel, the company—owned by Mars, Incorporated—claims to have sold some 400,000 tests—with the latest consumer version selling for $84.99 a pop. Its other major competitor is DNA My Dog—owned by a Canadian firm—which charges $59.99 per test. Both claim to unlock the mysteries of a dog's genes to reveal their breeds.Dogs are plagued by the greatest number of documented, naturally occurring genetic disorders of any non-human species. Donald Patterson, professor of medical genetics at the University of Pennsylvania, has maintained the Canine Genetic Disease Information System for the past 20 years, amassing a database that has grown to include over 370 genetic diseases in 200 dog breeds, with 5 to 10 new disorders added each year.